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br Experimental section br Results br Discussion In our prev
2020-07-08
Experimental section Results Discussion In our previous work (Rashidi et al., 2018) we isolated a novel glucarpidase whose raised NU 1025 did not cross-react with the one in clinical use. In principle, therefore, it would be possible to delay the production of antibodies in a patient by al
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The performance of the qCPA approaches is similar
2020-07-08
The performance of the qCPA approaches is similar with regards to the derivative properties of CO2 and for mixtures of CO2+self-associating compounds. For CO2+n-alkanes the four-parameter versions of qCPA both perform somewhat better than the three-parameter version. Nevertheless this modest improve
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br Discussion Of the age related
2020-07-08
Discussion Of the age-related differences in serum non-cholesterol sterols, we first deal with the cholesterol precursors. After birth, the markedly elevated serum desmosterol values decreased during the first year of life, and after 1 year of age they were similar between the other age groups. S
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The aim of the following work
2020-07-08
The aim of the following work was to untap the potential of DIS as a low-cost substrate for fungal production of lignocellulolytic enzymes via SSF. Fungal strains with the ability to transform the unpretreated DIS to a mixture of industrially relevant lignocellulases were identified. Furthermore, th
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Moreover a ligand for fusin has recently been
2020-07-07
Moreover, a ligand for fusin has recently been found: the lymphocyte chemoattractant stromal-derived factor-1 (SDF-1) binds to CHO Domiphen Bromide mg transfected with fusin and promotes secondary messenger production (Bleul et al., 1996; Oberlin et al., 1996). A new name, CXCR-4, has been proposed
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The physiological role of the UCNs in the
2020-07-07
The physiological role of the UCNs in the regulation of the HPA axis is still under debate (Fekete and Zorrilla, 2007, Suda et al., 2004). UCN 1 was proved to increase the plasma ACTH and corticosterone levels in rats (Bagosi et al., 2014, Vaughan et al., 1995), whereas UCN 2 and UCN 3 were shown to
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br Introduction Phoenixin PNX is a recently discovered pepti
2020-07-07
Introduction Phoenixin (PNX) is a recently discovered peptide produced mainly in hypothalamus by proteolytic cleavage of a small integral membrane protein 20 (Smim20) [1]. The most important endogenous active isoforms of PNX are amided peptides, composed of 14 and 20 glycerol phosphate [2]. Prev
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br Disclaimer Statement br Introduction The erythropoietin
2020-07-07
Disclaimer Statement Introduction The erythropoietin-producing hepatoma (Eph) receptors represent the largest class of receptor tyrosine kinases (RTKs). They are type I transmembrane proteins that interact with their membrane-bound ligands the ephrins and facilitate cell-to-cell contacts resul
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In rodents Wang et al
2020-07-07
In rodents (Wang et al., 2003, Wang and Tsirka, 2005b, Zhu et al., 2012) and humans (Wang et al., 2011), the major forms of cell death after ICH are necrosis and apoptosis. In the perihematomal region of rodents, the number of necrotic and apoptotic cells peaks at 72h post-ICH (Matsushita et al., 20
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The different serotypes A G have unique receptors
2020-07-07
The different serotypes (A-G) have unique receptors to which they bind to produce the toxic effect on the nerve cells. (Lance, 2004, Rosetto et al., 2014). Intracellularly, the endopeptidase activity of different serotypes of BoNT target selectively a unique group of proteins, the SNARE Valsartan (
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In regards to regional variation in metabolic behavior
2020-07-07
In regards to regional variation in metabolic behavior of adipose tissue, subcutaneous adipose tissue transplantation has been shown to reprogram visceral adipose tissue to have subcutaneous-like phenotypic behavior, whereas visceral-to-subcutaneous transplantation does not promote a more detrimenta
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To further define the importance of CYP A for OSC
2020-07-07
To further define the importance of CYP3A for OSC metabolism in vivo, a strong CYP3A inhibitor ketoconazole was used to test whether CYP3A would affect its metabolism. As expected, the biotransformation of OSC to SC was significantly decreased by ketoconazole at all three substrate concentrations. H
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Immune Response and Immune Evasion Up
2020-07-07
Immune Response and Immune Evasion Up to 10% of the host Protease Inhibitor Cocktail (100X in DMSO, EDTA plus) are infected with EBV during acute infectious mononucleosis. Most of these cells are effectively cleared by the immune system, but some downregulate viral gene expression and differentiat
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Defensins are one major class
2020-07-07
Defensins are one major class of antimicrobial, cationic peptides that are released from byl719 and imbedded in the mucus layer on mucosal surfaces [45]. They can be categorized into two major families; α- and β-defensins. In humans there are two α-defensin members, defensin 5 (HD5) and defensin 6
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Flavonoids are most common and widely distributed group
2020-07-06
Flavonoids are most common and widely distributed group of natural phenolic compounds synthesized by plants that have varied effects on mammalian cell systems (Kumar and Pandey, 2013). Several studies demonstrate that flavonoids might be potent inhibitors of several protein kinases involved in vario
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