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In this report we characterized MRJP containing aggregates a
2021-10-02

In this report, we characterized MRJP-containing transketolase and other (glyco)proteins from honey. Honey glycoproteins demonstrated potent anti-C. elegans activity. It has been reported that molecules that kill C. elegans are likely to be toxic to parasitic nematodes (Burns et al., 2015). To exam
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GI 254023X synthesis Which is the preferred dimer
2021-10-02

Which is the preferred dimer configuration, the one corresponding to the active state or the one corresponding to the desensitized state? Umbrella sampling simulations of a pair of GluA2 LBDs, using distances at the top (proximal to the ATD) and the bottom (proximal to the TMD), indicate that the de
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Regarding the causative diseases of
2021-10-02

Regarding the causative diseases of ES, patients with unknown cause and those with encephalitis had significantly higher CSF levels of lumacaftor against GluN2B-NT2 and GluN2B-CT than the disease controls, but patients with genetic disorder and those with cortical dysplasia showed no significant di
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Introduction Since the development of the first
2021-10-02

Introduction Since the development of the first radioimmunoassay (RIA) to measure hormone levels in the late 1950s, for which Rosalyn Sussman Yalow was awarded the Nobel Prize for Medicine in 1977 (the second woman ever receiving it), the use of cisapride in molecular research has increased tremend
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br Conclusion br Methods br Introduction To
2021-10-01

Conclusion Methods Introduction To predict such topologies, several algorithms have been developed. Quadparser (QP), developed by the Balasubramanian group have taken an approach where sequences matching G≥nN≤mG≥nN≤mG≥nN≤mG≥n model in which the lengths of G-tracts are at least n and lengths
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We compared the mixotrophic growth of mutant DRHB and the
2021-10-01

We compared the mixotrophic growth of mutant DRHB1486 and the wild-type at different light intensities. The mutant grew at a similar rate as the wild-type at a low light intensity but much more slowly at a high light intensity (Fig. 3). Because the slr2094 mutant was unable to grow under photoautotr
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Previous studies have shown that ox LDL induced hepatic
2021-10-01

Previous studies have shown that ox-LDL-induced hepatic sinus dysfunction is the result of multiple pathways, multi-factorial regulation, and in the present study, we reported for the first time that ox-LDL regulates the basement membrane protein VN through the integrin αvβ5 pathway under high gluco
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Our results further indicate that
2021-10-01

Our results further indicate that low expression of p300/CBP in CRC is directly associated with poor clinical therapeutic outcome of 5-FU treatment, potentially providing a new set of biomarkers to predict chemo-sensitivity. Although the ability of low expression of p300/CBP to predict poor prognosi
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(±)-CPSI 1306 Several named antagonist ligands have fig
2021-10-01

Several named antagonist ligands have figured noticeably in preclinical studies, with proved clear ability to release neurotransmitters and having efficacy in preclinical animal models. Consequently, this has encouraged ongoing research on improved agents with potency, selectivity, and better drug-l
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In cancer cells HIF upregulates HK II expression by
2021-10-01

In cancer cells, HIF-1α upregulates HK-II expression by binding to the hypoxia-responsive element in the HK-II promoter region to adapt to hypoxic conditions [20]. In the present study, we observed that mangiferin transiently increased HIF-1α expression in endothelial cells, suggesting another possi
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New follicular wave emergence is associated closely with the
2021-10-01

New follicular wave emergence is associated closely with the stage of the estrous Tianeptine sodium (Sirois and Fortune, 1988). As indicated by results from the present experiment, cows that had regression of the largest follicle on Day 0 of treatment onset had follicle wave characteristics that we
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Entry into CNS is tightly regulated by
2021-10-01

Entry into CNS is tightly regulated by highly dynamic barriers, namely, the BBB, the blood-CSF barrier, and the arachnoid epithelium (Abbott et al., 2010; Yasuda et al., 2013). Similar barriers also exist within the CNS including the ependymal barrier as well as the cellular membrane barriers of the
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br Conclusion br Conflict of interest
2021-10-01

Conclusion Conflict of interest Acknowledgments This work was supported by an NRF grant (2016R1A2B4011196) from the Korea Research Foundation. Introduction Thymic epithelial tumors are rare, but they are the most common primary neoplasm of the thymus and of the anterosuperior mediastinu
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Using data from a large population based cohort
2021-10-01

Using data from a large population-based cohort study in Finnish males and females, Suchankova et al. [97] looked at a subset of the aforementioned SNPs, namely one SNP on GHSR (rs2948694) and two SNPs on GHRL (rs4684677 and rs696217), in relation to alcohol use disorders identification test (AUDIT)
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So far several methods have
2021-10-01

So far, several methods have been used to monitor the level of GJC and its regulation in astrocytes studied in acute Biocytin slices (see Giaume et al., 2012). This mainly includes approaches based either on electrophysiological properties of gap junction channels or on “dye coupling” experiments t
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