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The central problem in amnesia developing following impairme
2024-10-08
The central problem in amnesia developing following impairment of long-term memory consolidation or reconsolidation is a question of the underlying mechanisms, whether it is caused by impairment of retrieval or memory storage mechanisms [3,8,9,[15], [16], [17], [18]]. To answer this question, severa
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Neural progenitor cells NPCs are self
2024-10-08
Neural progenitor cells (NPCs) are self-renewing, multipotent cells that are capable of differentiating into neurons, astrocytes and oligodendrocytes. NPCs are activated in response to a variety of pathological states in neurodegenerative diseases such as Parkinson’s disease and multiple sclerosis,
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Some alterations in the integrity of
2024-10-08
Some alterations in the integrity of cell membranes caused by toxic agents can be determined by measuring certain enzymes released by damaged cells [8]. The cholinesterases, for example, catalyze the hydrolysis of SQ 29,548 (ACh) in choline and acetic acid. Theses enzymes are divided into two types
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PL for actin in vitro showed that its profiles
2024-10-08
PL for ARM1 in vitro showed that its profiles, including particular peak and intensity, could determine the length and thickness of an actin filament. Furthermore, we investigated if the PL intensity peak at approximately 340 nm can also be originated from another cytoskeleton filament, such as mic
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There are several reports about
2024-10-08
There are several reports about the expression of AChRs and their modulation to osteogenic factors in osteoblasts (Rothem et al., 2011, Sato et al., 2010, Walker et al., 2001). The normal osteocytic MLO-Y4 abnormal lipid metabolism expressed multiple subtypes, which was demonstrated by the detection
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It is important http www apexbt com media
2024-10-08
It is important to note that the administration of THA significantly increased the area immunostained by the anti-pVEGFR2 antibody in medial septal cholinergic neurons. The same treatment slightly increased the expression levels of VEGFR2 in cholinergic neurons; however, this change was not confirme
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The next level of possible correlation
2024-10-08
The next level of possible correlation and comparison between the α7 and 5HT3 receptors is at the subunit arrangement and protein folding. Crystal structures of the nicotinic and serotoninergic Q-VD(OMe)-OPh australia receptors [45], [46] reinforced the concept of similarities between these familie
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br Results br Discussion Although
2024-10-08
Results Discussion Although they do not have protein-coding capacity, lncRNAs make up a large part of the transcripts of the genome, and they play fundamental roles in carcinogenesis and osteosarcoma progression through regulation of tumor proliferation and metastasis. These lncRNAs include M
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Phos-tag Song et al reported series of triazolylsalicylamide
2024-10-08
Song et al. reported series of 1,2,3-triazolylsalicylamide derivatives and screened over kinase panel and found compound 31 as most potent which inhibited Aurora-A, specifically with IC50 of 0.37 μM. Compound 31 was about 10-fold more active for Aurora-A than for Aurora-B (IC50 = 3.58 μM reported se
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Rizatriptan Benzoate br Introduction Increased renin angiote
2024-10-08
Introduction Increased renin-angiotensin system (RAS) activity and inflammation in cardiovascular-related regions of the central nervous system contribute to the overactivity of neurohumoral systems that promote volume retention, cardiac remodeling and serious cardiac arrhythmias in systolic hear
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Ginsenosides are the major bioactive constituents of the Pan
2024-10-03
Ginsenosides are the major bioactive constituents of the Panax ginseng root, which contain many types of ginsenosides including Rb1, Rg1, Rc, and Rg3. The ginsenoside Rb1 appears to be the most abundant of the bioactive ginsenosides [15]. Rb1 exhibits antiinflammatory, anticarcinogenic, and antioxid
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PKA signalling in the http www apexbt com media diy
2024-10-03
PKA signalling in the nucleus was thought to be due to the translocation of the catalytic subunit upon activation from the hrv3c cleavage site to the nucleus via diffusion [72]. However, a new understanding has emerged, as both the regulatory and catalytic subunits have been identified in the nucle
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We observed PACAP immunoreactivity in the molecular layer
2024-10-03
We observed PACAP2 immunoreactivity in the molecular layer of the cerebellar cortex in zebrafish. This result is consistent with the reporting of PACAP immunoreactivity in the soma and fibers of Purkinje cells and the presence of PACAP mRNA in the Purkinje-cell and granular-cell layers in rats [43].
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Nutritional factors affecting ASD have
2024-10-03
Nutritional factors affecting ASD have also recently received attention. An increase in postsynaptic zinc (Zn) level induced by clioquinol (a Zn chelator and ionophore), and the subsequent activation of NMDA receptors through the tyrosine kinase Src, rescued social interaction in Shank2−/− mice (Lee
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Owing to efficient catalytic character high electrolyte acce
2024-10-03
Owing to efficient catalytic character, high electrolyte accessible area, easy fabrication and many other interesting properties, metal oxide nanoparticles are extensively used in a variety of electro-analytical processes [14]. Metal oxide nanoparticles immobilized over a conductive and large area s
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