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br Conclusion br Acknowledgements br Introduction Tapentadol
2018-10-22
Conclusion Acknowledgements Introduction Tapentadol hydrochloride (TAP) (Fig. 1) is agonists of the μ-opioid receptor are being utilized expectedly for the treatment of moderate to serious agon. It is novel centrally-acting oral analgesic. Chemically it is 3-[(1R, 2R)-3-(dimethyl amino)-1-e
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Other differential diagnosis was made with lymphoreticular
2018-10-22
Other differential diagnosis was made with lymphoreticular malignancies such as lymphomas, Hodgkin\'s disease, malignant histiocytosis and monocytic leukaemia, all of which have similar histopathological features. Atypia in focal adhesion kinase and the aggressive clinical course establish the diag
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There contain two particular mitochondrial chaperone systems
2018-10-22
There contain two particular mitochondrial chaperone systems that boost the newly synthesized or imported proteins folding in the matrix. mtHSP70, part of presequence translocase associated import-motor (PAM) complex, and polymer HSP60/HSP10 (chaperonin60/10) as main machinery, which is evolutionary
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br Research by design An academic discourse
2018-10-22
Research by design An academic discourse is ongoing, and increasing attention is paid to the possible roles of design in research, commonly referred to as Research by Design (RbD). A conference entitled “Research by Design,” held at TU Delft in cooperation with the EAAE/AEEA in 2000, is regarded
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Introduction A great variation in
2018-10-22
Introduction A great variation in nursing homes exists across the world. In general, nursing homes provide an alternative place of residence, where 24-h care and assistance is offered by professional caregivers when people can no longer reside in their own home environment due to increasing need fo
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Convexity intraosseous meningiomas most commonly present as
2018-10-22
Convexity intraosseous meningiomas most commonly present as slowly growing scalp masses, with possible relationship to a cranial suture. Intraosseous meningiomas are mostly characterized by osteoblastic or mixed osteoblastic–osteolytic lesions, with purely lytic lesions being the least reported in i
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br Introduction br Case Report A year
2018-10-22
Introduction Case Report A 42-year-old woman had been treated for hypertension and arrhythmia for years. She visited our hospital complaining of chest pain with worsening nrf2 keap1 and dyspnea (New York Heart Association Class III) on exertion for 3 months. Examinations on admission revealed
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br Materials and methods br Results and discussion br Conclu
2018-10-22
Materials and methods Results and discussion Conclusion India has enormous varieties of underutilized fruits that vary in appearance and organoleptic features as well as presence of varieties of bioactive compounds. The delicious sweet fruits as well as the seeds of M. hexandra (Roxb.) Duba
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br Results br Discussion Recent advances
2018-10-22
Results Discussion Recent advances enabling the prospective isolation of mouse satellite am630 have facilitated mechanistic analyses of their myogenic function. For example, the ability to clonally sort satellite cells with high purity made possible the demonstration that these cells can unde
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To better characterize the Carnegie stage primate PGCs
2018-10-22
To better characterize the Carnegie stage 23 primate PGCs, we performed immunofluorescence for the basement membrane protein Laminin and the PGC marker OCT4 (Figure 2A). All OCT4-positive PGCs were located within the Laminin-positive cords in the testicular cortex at this age. We also discovered tha
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br Experimental Procedures br Author Contributions br Acknow
2018-10-22
Experimental Procedures Author Contributions Acknowledgments This work was supported in part by the Novel Bioengineering and Technological Approaches to Solve Two Major Health Problems in Taiwan sponsored by the Taiwan Ministry of Science and Technology Academic Excellence Program under gra
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So far literature on A R has been in
2018-10-22
So far, literature on A1R has been in favor of a prevailing role played by these receptors in the activation of osteoclasts (Kara et al., 2010; He and Cronstein, 2012) and some findings showed that the blockade of these AR may induce favorable effects on osteoporosis or fracture healing. However, ou
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M macrophage derived factors such as FGF
2018-10-20
M2 macrophage-derived factors, such as FGF2, IGF-1, PDGF, TGFβ1 and VEGF are angiogenic, limiting cell death due to lack of blood supply (Nakao-Hayashi et al., 1992; Nahrendorf et al., 2007; Grant et al., 1993b; Roberts et al., 1986). Angiogenesis is also supported by M2 macrophage production of ECM
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domoic acid Although both c Kit Lin and Sca Lin have been
2018-10-20
Although both c-Kit+Lin− and Sca-1+Lin− have been shown to be undifferentiated cardiac cells with differentiation ability, a clear difference seems to have been established between these cells at the molecular level (Dey et al., 2013). A study of their transcriptional profiles revealed that c-Kit+ r
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The PBMC iPS F cell line has been adapted to
2018-10-20
The PBMC1-iPS4F1 cell line has been adapted to feeder-free culture conditions and displays a normal karyotype (46, XX) after extensive mechanical and enzymatic transfers (Fig. 1D). The iPSC line was also characterized using a genetic fingerprinting assay by microsatellite analysis. The endogenous e
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