• We also found clear differences in the amount of stress

  2018-10-31

  

  We also found clear differences in the amount of stress fibers between the perivascular derivatives. Abundant stress fibers were found in con-vSMCs located throughout the entire cell body. While hiPSC syn-vSMCs had fewer stress fibers, pericyte derivatives demonstrated the lowest levels of stress fi

• In their letter Sadek et

  2018-10-31

  

  In their letter, Sadek et al. refer to other studies showing robust and reproducible regeneration. However, none of the studies published to date (Haubner et al., 2012; Heallen et al., 2013; Jesty et al., 2012; Naqvi et al., 2014; Strungs et al., 2013) actually performed apex resection on postnatal

• Introduction Cell to cell competition among male germline st

  2018-10-31

  

  Introduction Cell-to-cell competition among male germline stem cells has been proposed to account for the higher frequency of some disorders among children of older fathers, a correlation referred to as the paternal age effect (PAE) (Goriely and Wilkie, 2012). In addition to compelling observations

• It is intriguing that all surviving germ cells in

  2018-10-31

  

  It is intriguing that all surviving germ cells in Ret mutant mice expressed GFRA1. It is possible that GFRA1 was upregulated to compensate for the reduction of GDNF signaling. Because of the controversy on GFRA1 expression on SSCs, we performed FACS experiments to explore the relationship between GF

• br Materials and methods br Results

  2018-10-31

  

  Materials and methods Results Discussion Several in vivo and in vitro studies indicate that OPCs have substantially different properties according to their chronological age. For example, human fetal OPCs from different gestational stages exhibit differences in the myelination profile (Cui

• Main Text The field of stem cell research has

  2018-10-31

  

  Main Text The field of stem cell research has continued to advance at a terrific pace over the past year, with continued improvements in technology allowing us to interrogate the pathways underpinning development, injury, and repair of our cells, tissues, and organs. We have seen leaps forward in t

• Neuroanatomical studies indicate that DARPP neurons could

  2018-10-31

  

  Neuroanatomical studies indicate that DARPP32+ neurons could be divided into two populations: one that constructs a direct pathway and another that constructs an indirect pathway. DARPP32+ neurons in the direct pathway express DRD1 and are located in the striosome. On the other hand, those in the in

• Induced pluripotent stem cell iPSC technology holds great pr

  2018-10-31

  

  Induced pluripotent stem cell (iPSC) technology holds great promise for future autologous cellular therapies for vascular diseases (Tavernier et al., 2013). However, a major concern is the availability of approaches to differentiate iPSCs into large quantities of functional VSMCs for research and th

• Spectral analysis was used to

  2018-10-30

  

  Spectral analysis was used to identify the segments of the strainmeter recordings where the period coincided with the period during which the transducer operated in the sea. Fig. 3 shows synchronous dynamic spectrograms of the recordings of the complex phase-shift signal by the reference hydrophone

• br Conclusions br Conflict of interest br Ethical standards

  2018-10-30

  

  Conclusions Conflict of interest Ethical standards Financial support This work was supported by Grant-in-Aid for Scientific Research on Innovative Areas (Grant number 20616784; Adolescent Mind & Self-Regulation) from the Ministry of Education, Culture, Sports, Science and Technology of J

• adenosine receptor agonist However caution is warranted in s

  2018-10-30

  

  However, caution is warranted in suggesting social and emotional support as the causal mechanism promoting improved infant birth outcomes for midwifery patients. To date, numerous observational studies have examined social support interventions in relation to adverse pregnancy outcomes (Orr, 2004),

• Low household income and educational attainment are associat

  2018-10-30

  

  Low household income and educational attainment are associated with material deprivation and reduced opportunities for children that plk inhibitor in turn predict the onset and severity of childhood mental health problems (Evans, 2004; McLaughlin et al., 2011; Reiss, 2013). However beyond material

• Peri operative use of opioid analgesic medications

  2018-10-30

  

  Peri-operative use of opioid analgesic medications-including Patient controlled analgesia (PCA) further increases the risk of such complications [5,6]. Prevention of these adverse events may be made possible by appropriate post-operative SPo2 and Etco2 monitoring [7]. O2 supplementation is required

• Airway epithelial cells present as one of the first

  2018-10-30

  

  Airway epithelial cells, present as one of the first lines of defense for inhaled particulate matter, represent a major determinant in the interaction of a foreign body with other major body compartments. In addition, epithelial mixed-methods are involved with the formation and maintenance of tight

• br Conclusions br Introduction Safety concerns

  2018-10-30

  

  Conclusions Introduction Safety concerns about food, drinking water, health surveillance, and clinical diagnosis related to microbial pathogens have attracted increasing attention worldwide. On the basis of tsa trichostatin structure and stain ability with gram stain (weakly alkaline solution

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