• Individual level studies of sense of place have lacked

  2018-11-05

  

  Individual-level studies of sense of place have lacked conceptual cohesion, coming under various guises including ‘place attachment’ (Hidalgo & Hernandez, 2001; Scannell & Gifford, 2010), ‘sense of community’ (Gattino et al., 2013), and ‘sense of place’ (Pretty, Chipuer, & Bramston, 2003; Williams &

• These findings come from the discipline of evolutionary

  2018-11-05

  

  These findings come from the discipline of evolutionary psychology, which has also analyzed its subjects’ decision-making behaviour as write (Griskevicius & Kenrick, 2013), meaning their financial decisions and their choices about consumption, working on the principle that the human mind is the prod

• Introduction Regarding acid mine drainage AMD the high

  2018-11-05

  

  Introduction Regarding wee1 mine drainage (AMD), the high concentrations of heavy metals cause major environmental concerns characterized by contamination of various ecosystems due to its leaching capacity and the presence of very active bacteria making it self-perpetuating (Kalin et al., 2006). T

• Introduction Raw water in South Africa is considered

  2018-11-05

  

  Introduction Raw water in South Africa is considered a strategic national resource, with the responsibility for its management taking place at three tiers. These are firstly Central Government, secondly Provincial and Regional Governments, including other specified authorities, and thirdly Local Au

• This specificity suggests the possibility of tailoring algal

  2018-11-05

  

  This specificity suggests the possibility of tailoring algal phycoremediation processes to suit specific contaminant conditions, as well as the possibilities for enhancing both uptake limits and uptake specificity through genetic engineering of algal species. The down side of active approaches invol

• br Methods br Results br Discussion Sequencing of the

  2018-11-05

  

  Methods Results Discussion Sequencing of the first human genome took more than a decade, completing in 2001, and costing more than US$2.7 million (Lander et al., 2001; Venter et al., 2001; NHGRI, 2010). In the subsequent decade, newer high-throughput genomic technologies, known as the Next-

• From studies with mouse models Huber Lang et al

  2018-11-05

  

  From studies with mouse models (Huber-Lang et al., 2006; Hoth et al., 2014; Khan et al., 2013; Auger et al., 2012; Zecher et al., 2014; Borkowska et al., 2014), several groups have concluded that thrombin is the major coagulation enzyme that generates C5a under pathologic conditions. This role for t

• A substantial proportion of variants identified

  2018-11-05

  

  A substantial proportion of variants identified (12.5% familial; 11% sporadic) were not classifiable based solely on RNA analysis as functionally relevant. Nonetheless several of those reported here have been shown to be disease causing by functional analysis and other evidence such as being proven

• br Materials and Methods br Results br Discussion

  2018-11-05

  

  Materials and Methods Results Discussion PDGF-BB/PDGFR-ββ signaling is a druggable target whose inhibition mitigates liver fibrosis severity (Liu et al., 2011). Several strategies to block PDGF-BB/PDGFR-ββ signaling have been applied in scientific research on liver fibrosis. For instance, P

• Several conflicting large scale population based studies

  2018-11-05

  

  Several conflicting large-scale population-based studies published recently (e.g. (Lau et al., 2015; Moriya et al., 2015; Tsunoda et al., 2014)) indicated that p-selectin moderate (or ‘non-alcoholic’) alcohol consumption either has a beneficial or detrimental association with prevalence or developme

• br Relationship of Fatty Liver

  2018-11-05

  

  Relationship of Fatty Liver with the Metabolic Syndrome Traditionally deemed to be the “hepatic manifestation of the metabolic syndrome”, NAFLD is more correctly deemed to be bi-directionally linked with either the Metabolic Syndrome (MetS) or its individual components. Indeed, on the one hand me

• br The recent meta analysis in by Shen and colleagues

  2018-11-05

  

  The recent meta-analysis in by Shen and colleagues is the first to report a systematic analysis of the diagnostic performance of bronchoalveolar lavage fluid (BALF) CD4/CD8 ratios in sarcoidosis (). Their results are consistent with numerous studies and BAL guidelines over the last 2 decades which

• br The recent meta analysis in by Shen and colleagues

  2018-11-05

  

  The recent meta-analysis in by Shen and colleagues is the first to report a systematic analysis of the diagnostic performance of bronchoalveolar lavage fluid (BALF) CD4/CD8 ratios in sarcoidosis (). Their results are consistent with numerous studies and BAL guidelines over the last 2 decades which

• hiv protease Small cell lung cancer SCLC accounts for

  2018-11-05

  

  Small-cell lung cancer (SCLC) accounts for about 15% of all lung tumors and has a 5-year survival below 5%. While SCLC tumors are initially sensitive to chemotherapy, they invariably relapse with a resistant and deadly disease. We and others have found that, contrary to lung adenocarcinomas and squa

• order T-5224 br Methods br Results br

  2018-11-05

  

  Methods Results Discussion Insufficiency of GCase activity in order T-5224 due to GBA1 gene mutations is the molecular mechanism of GD. However, it has been observed that patients with the same GCase mutations may have significant variably in disease presentation, from a life-threatening m

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