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br Materials and methods br Author disclosure statement
2018-11-06
Materials and methods Author disclosure statement 5. Acknowledgments This work was supported by the UK Medical Research Council grants G0701172 and G0801061. We thank Dr. Yacoub Khalaf, director of the Assisted Conception Unit of Guy\'s and St. Thomas\' NHS Foundation Trust and his staff fo
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Based on the differentiation and siRNA studies reported
2018-11-06
Based on the differentiation and siRNA studies reported here, the mechanistic regulation of FOXM1 towards pluripotency control and differentiation might differ between mouse and human ES cells. The discrepancy can be attributed to the different developmental status of human versus mouse ES cells (Ni
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The sorted BMSC and HSPC populations were observed
2018-11-06
The sorted BMSC and HSPC populations were observed to exist in distinct states of the cell cycle, equally important for their functions as stem cells. The MG-132 gene expression studies further ascertained the cellular physiology of both the sorted cell populations. Our results also coincide with s
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br Materials and methods br
2018-11-06
Materials and methods Results Discussion Others and we have demonstrated that ESC-based developmental modeling mimics a variety of neurodevelopmental events occurring in vivo using either 2-D or 3-D systems. In those studies, the hESC-based developmental model has been proposed to imitate e
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Background green fluorescence was detected in the lentiviral
2018-11-06
Background green fluorescence was detected in the lentiviral reprogrammed MML-6838-CL2 iPSC line and a control episomal (non-GFP) reprogrammed iPSC, indicating silencing (Fig. 1B). Pluripotency was confirmed by detecting expression of SOX2, OCT4, SSEA4, TRA1-61 and TRA1-80 pluripotency-associated ma
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In summary our results have
2018-11-05
In summary, our results have shown that Notch signaling could inhibit the expression of miR-342-5p. In NSCs where Notch signaling is activated, the level of miR-342-5p is low and NSCs maintain the potential to differentiate into GFAP-positive astrocytes. When some NSCs gradually differentiate into I
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br Introduction Hematopoietic stem cells HSCs persist
2018-11-05
Introduction Hematopoietic stem n-acetyl-l-cysteine (HSCs) persist throughout life to produce hematopoietic progenitor cells (HPCs) and all types of blood cells. In the adult, HSCs reside in bone marrow (BM), are rare but have the unique capability for self-renewal and multilineage differentiati
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br Experimental Procedures br Author Contributions
2018-11-05
Experimental Procedures Author Contributions Acknowledgments This study was supported by the UCR Initial Complement Fund and the UCR Stem Cell Core Facility, funded by CIRM. Introduction Since the advent of cellular reprogramming with exogenous transcription factors (Takahashi et al., 2
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their mathematical expectations follow the
2018-11-05
their mathematical expectations follow the expressions According to the CLT for independent random variables , for N → ∞ the expression tends to a standardized Gaussian random variable. Therefore for N ≫ 1 we have the following approximate equalities: where θ0, , are the standardized Gaussian
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br The current of inelastically scattered electrons
2018-11-05
The current of inelastically scattered electrons is determined by the density matrix The angular brackets in the right-hand side of equality (9) correspond to averaging over the distribution of the scattering centers. If inelasticity is not connected to the excitation of the force centers by w
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br Problem setting PS M V
2018-11-05
Problem setting PS1-M146V, a presenilin model implying the presence of a mutation in the gene encoding the presenilin protein [7]; APPKI, an amyloid model implying the presence of a mutation in the gene encoding APP [9]. Recently, our laboratory has developed one more model which, in ampa with
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Calculation scheme According to Buckingham
2018-11-05
Calculation scheme. According to Buckingham\'s theory for a system of two polar components, the following relationships hold true: where ε is the dielectric permittivity; n is the refractive index; V is the molar volume, V= ( is the specific volume; М is the molecular weight); х is the molar fract
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However prior studies have not specifically examined neighbo
2018-11-05
However, prior studies have not specifically examined neighborhood racial composition or density in association with pregnancy-related weight such as weight prior to pregnancy and gestational weight gain, and the potential intersections with individual race and neighborhood income or poverty. One pr
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Our original contribution to the literature is threefold Fir
2018-11-05
Our original contribution to the literature is threefold. First, the study uses the 12-item GHQ-12 as separate items instead of considering them as a summary score. To our knowledge, it is the first time that this has been attempted within the field of social capital. Employing as dependent variable
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I-BET-762 Supplier The type of occupation of
2018-11-05
The type of occupation of an individual may influence the place of death. We found that I-BET-762 Supplier most of the adult deaths occurred among those with elementary occupations, closely followed by those in agricultural and fishery occupations. However, with the exception of the skilled agricult
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