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Studies have also looked at the development of reappraisal i
2018-11-09
Studies have also looked at the development of reappraisal in the regulation of appetitive cravings for unhealthy foods (Silvers et al., 2014; Giuliani and Pfeifer, 2015). In a recent study, females aged 10–23 were asked to use reappraisal to reduce cravings (Giuliani and Pfeifer, 2015). Across all
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Interestingly PPN cells with N type channels only
2018-11-09
Interestingly, PPN Asiatic acid with N-type channels only manifested oscillations in the 50Hz range, while cells with P/Q-type channels only exhibited oscillations in the 45Hz range, while cells with both N- and P/Q-type channels showed oscillations in the 37Hz range. These results suggest that eac
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Second specifically talking on labor markets Marx singled
2018-11-09
Second, specifically talking on labor markets, Marx singled out that coelenterazine workers had to go beyond (1975, 78 and 79): Conclusion Introducción El concepto de innovación inclusiva tiene su origen en lo que se llamó el desarrollo de la tecnología apropiada con la idea de elaborar alte
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Bisindolylmaleimide V According to several studies hotspots
2018-11-09
According to several studies, hotspots of RAS mutations have been identified in codons 12, 13, 59, 61, 117, and 146, which are considered to induce conformational changes into constitutively active forms (Prior et al., 2012; Smith et al., 2010). In addition, these gene mutations tend to occur in a m
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In addition to these benefits growing SFEBs on
2018-11-08
In addition to these benefits, growing SFEBs on MIs has similar advantages to organotypic slice culture preparations. Brain slice cultures allow maximal flexibility when performing both electrophysiological and imaging experiments (Thompson et al., 2006). The protocol outlined here is particularly u
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Unfortunately existing cytogenetic karyotyping methods are
2018-11-08
Unfortunately, existing cytogenetic karyotyping methods are labor intensive, requiring at least 15 fixed metaphase preparations, subsequent DAPI staining, and analysis with an epi-fluorescence microscope equipped with specialized digital imaging software. Conventional karyotyping is expensive (∼$400
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Translational controls have a central role in the regulation
2018-11-08
Translational controls have a central role in the regulation of stem cell biology. The importance of translational regulations has been reported in mouse embryonic stem cells, which display a considerable increase in mRNA levels and translation during their differentiation (Sampath et al., 2008). In
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Induced pluripotent stem cells iPSCs have the
2018-11-08
Induced pluripotent stem daunorubicin (iPSCs) have the characteristics of human embryonic stem cells (hESCs), and many studies have investigated the similarities between iPSCs and hESCs, including genome stabilities, transcriptome (Chin et al., 2009; Guenther et al., 2010; Newman and Cooper, 2010; W
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br Materials and methods br Results br
2018-11-08
Materials and methods Results Discussion An interesting discovery was that mTORC1 did not affect neurite density, as measured by neurite length divided by number of neurons, in the initial period in neuronal differentiation. Considering that the number of neurons did not change over time bu
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LY2857785 We found seven published clinical
2018-11-08
We found seven published clinical trials studying the effects of MSC transplantation in patients with liver cirrhosis (listed in Table 2). A pilot phase 1 study published in 2007 included four patients with decompensated liver cirrhosis (Mohamadnejad et al., 2007). Cells were derived from iliac cre
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To further examine the influence of microgravity mechanical
2018-11-08
To further examine the influence of microgravity mechanical unloading on differentiation of mesenchymal and hematopoietic lineages, we investigated genes associated with terminal differentiation of these lineages. We found a broad down-regulation of early to mid stage differentiation markers and dow
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Because SAPK mediates hyperosmolar stress induced Hand
2018-11-08
Because SAPK mediates hyperosmolar stress-induced Hand1 and Hand1-dependent PL1 (Awonuga et al., 2011), we tested whether stress-induced lineage choice during hypoxia was SAPK-dependent. Since hyperosmolar stress induces the first lineage but not later lineages from TSC (Liu et al., 2009), and SAPK
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Introduction The loss of retinal neurons their connections
2018-11-08
Introduction The loss of retinal neurons, their connections and supporting glia in ocular degenerative diseases causes permanent blindness, principally because lost photoreceptors and retinal ganglion cells (RGCs) are not replaced and RGC LDE225 fail to regenerate (Berry et al., 2008). Clinically,
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Taken together our findings support the hypothesis that AM
2018-11-08
Taken together, our findings support the hypothesis that AM can rescue OPC differentiation via receptor-mediated Akt signaling. However, there are some important caveats to keep in mind. First, our current study used only a pure cell culture system. However, to prove clinically-relevant supportive/p
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br Materials and methods br Results br
2018-11-08
Materials and methods Results Discussion We have previously shown that cellular phenotype is an important determinant of the malignant potential in human neuroblastoma chronic health condition and tumors (Walton et al., 2004). In particular, in those experiments, we identified a stem cell
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